Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782797 | 0.89 | PIK3CA (0.42) | PIK3CAMTORPIK3R1DRD2DRD1 | |
| SCHEMBL4782301 | 0.87 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4846093 | 0.87 | HRH4 (0.44) | PIK3CAMTORPIK3R1ADORA3ADORA1 | |
| SCHEMBL4785845 | 0.87 | HRH4 (0.44) | PIK3CAMTORPIK3R1ADORA3ADORA1 | |
| SCHEMBL4784093 | 0.87 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CGALDH1A1 | |
| SCHEMBL4783926 | 0.87 | HRH4 (0.44) | PIK3CAMTORPIK3R1ADORA3ADORA1 | |
| SCHEMBL4782727 | 0.86 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4884098 | 0.86 | PIK3CA (0.45) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4784166 | 0.86 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4785240 | 0.86 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |