Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 17/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220485 | 0.96 | PTPN1 (0.43) | PTPN1CNR1CNR2PTPN22 | |
| SCHEMBL3222948 | 0.95 | PTPN1 (0.41) | PTPN1CNR1CNR2 | |
| SCHEMBL2936381 | 0.92 | PTPN1 (0.40) | PTPN1CNR1CNR2PTPN2PTPRA | |
| SCHEMBL2936384 | 0.92 | PTPN1 (0.39) | PTPN1CNR1CNR2 | |
| SCHEMBL3201537 | 0.89 | CNR1 (0.43) | PTPN1CNR1CNR2 | |
| SCHEMBL3217932 | 0.88 | CNR1 (0.41) | PTPN1CNR1CNR2PTPN2PTPRA | |
| SCHEMBL3216170 | 0.88 | PTPN1 (0.40) | PTPN1CNR1CNR2 | |
| SCHEMBL3216067 | 0.88 | CNR1 (0.42) | PTPN1CNR1CNR2 | |
| SCHEMBL3929110 | 0.87 | CNR1 (0.41) | PTPN1CNR1CNR2 | |
| SCHEMBL2930479 | 0.86 | CNR1 (0.41) | PTPN1CNR1CNR2PTPN2PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008067527-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS | NOVARTIS AG (CH) | 2008-06-05 | — | — | WO | disclosed |