SCHEMBL4784823 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	EPHX2	P34913	1/20	0.43

▸	KMT2A	Q03164	2/20	0.43

▸	DPP8	Q6V1X1	1/20	0.43

▸	DPP9	Q86TI2	1/20	0.43

▸	OPRD1	P41143	1/20	0.38

▸	MDM4	O15151	1/20	0.38

▸	TP53	P04637	1/20	0.38

▸	CASP3	P42574	2/20	0.38

▸	FABP7	O15540	1/20	0.38

▸	FABP5	Q01469	1/20	0.38

▸	ALDH1A1	P00352	1/20	0.38

▸	CTSS	P25774	4/20	0.37

▸	CTSK	P43235	4/20	0.37

▸	CTSL	P07711	3/20	0.37

▸	CTSB	P07858	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL178775	0.88	KMT2A (0.51)	EPHX2KMT2ADPP8DPP9MDM4
SCHEMBL30594472	0.88	KMT2A (0.51)	EPHX2KMT2ADPP8DPP9MDM4
SCHEMBL29624557	0.88	KMT2A (0.51)	EPHX2KMT2ADPP8DPP9MDM4
SCHEMBL555165	0.88	BACE1 (0.44)	EPHX2KMT2ADPP8DPP9MDM4
SCHEMBL6111714	0.87	EPHX2 (0.46)	EPHX2KMT2ADPP8DPP9OPRD1
SCHEMBL30594467	0.87	KMT2A (0.50)	EPHX2KMT2ADPP8DPP9CASP3
SCHEMBL29624551	0.87	KMT2A (0.50)	EPHX2KMT2ADPP8DPP9CASP3
SCHEMBL7401413	0.87	KMT2A (0.50)	EPHX2KMT2ADPP8DPP9CASP3
SCHEMBL29624561	0.87	KMT2A (0.50)	EPHX2KMT2ADPP8DPP9CASP3
SCHEMBL178786	0.87	KMT2A (0.50)	EPHX2KMT2ADPP8DPP9CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008080223-A1	COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE	MIGENIX INC. (CA)	2008-07-10	—	—	WO	disclosed