Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734348 | 0.90 | TACR1 (0.37) | ALDH1A1LMNAMAPTFASNHTT | |
| SCHEMBL4732368 | 0.85 | MCHR1 (0.41) | NPBWR1MCHR1SRD5A2FASNHTT | |
| SCHEMBL4730041 | 0.84 | NPBWR1 (0.42) | NPBWR1MCHR1MAPTSRD5A2HTT | |
| SCHEMBL4730905 | 0.83 | PPARD (0.42) | NPBWR1MCHR1PPARDRXRARXRB | |
| SCHEMBL4733671 | 0.81 | IRAK4 (0.41) | NPBWR1MCHR1 | |
| SCHEMBL12678453 | 0.80 | MEN1 (0.36) | ALDH1A1LMNAMAPTHTTPOLB | |
| SCHEMBL4735023 | 0.79 | TACR1 (0.44) | ALDH1A1MAPTHTTPPARDPOLB | |
| SCHEMBL5611221 | 0.79 | SRD5A1 (0.36) | MCHR1FASNHTTPOLBMEN1 | |
| SCHEMBL4729637 | 0.79 | MEN1 (0.46) | ALDH1A1HTTPPARDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4734121 | 0.79 | MEN1 (0.39) | ALDH1A1LMNAMAPTFASNHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057497-A2 | SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION | CURIS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |