Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571893 | 0.79 | KLK7 (0.54) | POLBKLK7HSD17B10MEN1MAPT | |
| SCHEMBL11175388 | 0.79 | POLB (0.50) | POLBKLK7SMN1; SMN2TSHRTP53 | |
| SCHEMBL9055691 | 0.79 | POLB (0.50) | POLBKLK7SMN1; SMN2TSHRTP53 | |
| SCHEMBL28568899 | 0.79 | KLK7 (0.54) | POLBKLK7HSD17B10MEN1MAPT | |
| SCHEMBL28387238 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2ALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL28387237 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2ALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL5696572 | 0.76 | KLK7 (0.51) | POLBKLK7SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL752740 | 0.76 | MME (0.43) | HSD17B10ALDH1A1CASP3MEN1MAPT | |
| Propham SCHEMBL8536412 | 0.76 | SMN1; SMN2 (0.66) | KLK7SMN1; SMN2TSHRTP53EPHX1 | |
| Propham SCHEMBL67344 | 0.76 | SMN1; SMN2 (0.66) | KLK7SMN1; SMN2TSHRTP53EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |