Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 12/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161661 | 1.00 | MTOR (0.48) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL14161665 | 0.93 | LMNA (0.42) | MTORPIK3CAPIK3CGPIK3CBKDM4E | |
| SCHEMBL4785193 | 0.88 | MTOR (0.43) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL14161775 | 0.88 | MTOR (0.43) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL14161660 | 0.84 | PIK3CA (0.47) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL4782727 | 0.83 | PIK3CA (0.58) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL4785240 | 0.83 | PIK3CA (0.58) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL4784922 | 0.81 | MTOR (0.48) | MTORPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL14161658 | 0.80 | MTOR (0.46) | MTORPIK3CAPIK3CGPIK3CB | |
| SCHEMBL14161858 | 0.80 | MAPT (0.46) | MTORPIK3CAPIK3CGPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |