Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813956 | 0.88 | MGLL (0.55) | TBXA2RLMNAMAPTHTTMEN1 | |
| SCHEMBL4787051 | 0.85 | TBXA2R (0.62) | TBXA2RMEN1KMT2AMGLL | |
| SCHEMBL4783512 | 0.85 | EPHX2 (0.49) | TBXA2RMEN1KMT2A | |
| SCHEMBL4228345 | 0.83 | MAPT (0.53) | TBXA2RLMNAMAPTHTTMEN1 | |
| SCHEMBL4786650 | 0.83 | TBXA2R (0.61) | TBXA2RMAPTMEN1KMT2A | |
| SCHEMBL4686742 | 0.83 | HTT (0.56) | LMNAMAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4686748 | 0.83 | HTT (0.56) | LMNAMAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4785961 | 0.82 | TBXA2R (0.59) | TBXA2RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4787176 | 0.81 | TBXA2R (0.57) | TBXA2RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4785116 | 0.81 | TBXA2R (0.58) | TBXA2RMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |