Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3322822 | 0.98 | NOS2 (0.42) | NOS2USP2TSHRMAPTABCC4 | |
| Hydrochloric Acid SCHEMBL3321961 | 0.96 | NOS2 (0.41) | NOS2USP2TSHRMAPTABCC4 | |
| SCHEMBL3322305 | 0.74 | TSHR (0.34) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL4737247 | 0.74 | TSHR (0.34) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL1240084 | 0.74 | TSHR (0.42) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL28311815 | 0.73 | TSHR (0.42) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL3324577 | 0.72 | TSHR (0.38) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL4737080 | 0.72 | TSHR (0.38) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL23234380 | 0.72 | TSHR (0.46) | USP2TSHRMAPTABCC4ALDH1A1 | |
| SCHEMBL21067372 | 0.72 | NOS2 (0.50) | NOS2TSHRANPEPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070733-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |