Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617008 | 0.92 | SFRP1 (0.83) | SFRP1WNT3 | |
| SCHEMBL4734853 | 0.88 | SFRP1 (0.78) | SFRP1WNT3 | |
| SCHEMBL4732071 | 0.87 | SFRP1 (0.77) | SFRP1WNT3 | |
| SCHEMBL4616144 | 0.86 | SFRP1 (0.85) | SFRP1WNT3 | |
| SCHEMBL4618305 | 0.86 | SFRP1 (0.77) | SFRP1WNT3 | |
| SCHEMBL4668451 | 0.86 | SFRP1 (0.77) | SFRP1WNT3 | |
| SCHEMBL4731977 | 0.85 | SFRP1 (0.87) | SFRP1WNT3 | |
| SCHEMBL4731974 | 0.85 | SFRP1 (0.87) | SFRP1WNT3 | |
| SCHEMBL4735498 | 0.85 | SFRP1 (0.86) | SFRP1WNT3 | |
| SCHEMBL4735911 | 0.85 | SFRP1 (0.54) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |