Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172082 | 1.00 | MAPT (0.37) | MAPTKDM4EALDH1A1TDP1EPHX1 | |
| SCHEMBL13884742 | 0.82 | SLC18A2 (0.32) | MAPTKDM4EALDH1A1TDP1EPHX1 | |
| SCHEMBL4746758 | 0.82 | HTT (0.44) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL3975545 | 0.82 | HTT (0.44) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL8171940 | 0.81 | CASR (0.39) | SLC1A3SLC1A2SLC1A1TACR1 | |
| SCHEMBL4088596 | 0.81 | CASR (0.39) | SLC1A3SLC1A2SLC1A1TACR1 | |
| SCHEMBL4743482 | 0.73 | TACR1 (0.34) | TACR1 | |
| SCHEMBL4551129 | 0.73 | TACR1 (0.38) | ALDH1A1TACR1 | |
| SCHEMBL13885022 | 0.72 | TDP1 (0.38) | KDM4EALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL8175955 | 0.71 | TDP1 (0.37) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |