Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427262 | 0.91 | TSHR (0.46) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL112994 | 0.89 | TDP1 (0.54) | TSHRPOLBHPGDMEN1KMT2A | |
| SCHEMBL919959 | 0.89 | TSHR (0.44) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL919432 | 0.89 | SMN1; SMN2 (0.46) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL919960 | 0.89 | HTR2A (0.54) | TSHRPOLBCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL919431 | 0.89 | TSHR (0.44) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL920930 | 0.89 | TSHR (0.49) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL598729 | 0.88 | TSHR (0.47) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL3082123 | 0.88 | SIGMAR1 (0.52) | TSHRMEN1KMT2A | |
| SCHEMBL28944039 | 0.87 | SLC6A2 (0.52) | TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147333-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-31 | — | — | WO | disclosed |
| WO-2008066980-A1 | PRODUCTION OF HIGH PURITY DECABROMODIPHENYLALKANES | ALBEMARLE CORPORATION (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080132743-A1 | PRODUCTION OF HIGH PURITY DECABROMODIPHENYLALKANES | ALBEMARLE CORPORATION (US) | 2008-06-05 | — | — | US | disclosed |
| WO-2008057645-A1 | PREPARATION OF HIGH ASSAY DECABROMODIPHENYLALKANE | ALBEMARLE CORPORATION (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080108855-A1 | PREPARATION OF HIGH ASSAY DECABROMODIPHENYLALKANE | ALBEMARLE CORPORATION (US) | 2008-05-08 | — | — | US | disclosed |
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |