Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161674 | 0.96 | PIK3CA (0.35) | PIK3CAPIK3R1ADORA3ADORA1MET | |
| SCHEMBL4784163 | 0.96 | PIK3CA (0.35) | PIK3CAPIK3R1ADORA3ADORA1MET | |
| SCHEMBL4785566 | 0.92 | CHRM3 (0.35) | PIK3CAPIK3R1ADORA3ADORA1CHRM3 | |
| SCHEMBL14161656 | 0.89 | PIK3CA (0.40) | PIK3CAPIK3R1MTOR | |
| SCHEMBL14161859 | 0.86 | PIK3CA (0.38) | PIK3CAPIK3R1CHEK1MTOR | |
| SCHEMBL4781444 | 0.83 | PIK3CA (0.35) | PIK3CAPIK3R1ADORA3ADORA1CHEK1 | |
| SCHEMBL4783926 | 0.83 | HRH4 (0.44) | PIK3CAPIK3R1ADORA3ADORA1MTOR | |
| SCHEMBL4846093 | 0.83 | HRH4 (0.44) | PIK3CAPIK3R1ADORA3ADORA1MTOR | |
| SCHEMBL4785845 | 0.83 | HRH4 (0.44) | PIK3CAPIK3R1ADORA3ADORA1MTOR | |
| SCHEMBL4784229 | 0.82 | PIK3CA (0.35) | PIK3CAPIK3R1CHEK1JAK2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |