Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161861 | 0.89 | LMNA (0.37) | PIK3CAPIK3R1PIK3CBPIK3CGPRMT5 | |
| SCHEMBL4785206 | 0.88 | KDR (0.42) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4786681 | 0.85 | POLB (0.40) | PIK3CAPIK3R1PRMT5WDR77MEN1 | |
| SCHEMBL4785152 | 0.83 | PIK3CA (0.37) | PIK3CAPDE5AMEN1LMNACYP1A2 | |
| SCHEMBL4785290 | 0.83 | PIK3CA (0.37) | PIK3CAPDE5AMEN1LMNACYP1A2 | |
| SCHEMBL14161656 | 0.83 | PIK3CA (0.40) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4785757 | 0.83 | PIK3CA (0.36) | PIK3CAPIK3R1MTORCHEK1JAK2 | |
| SCHEMBL14161674 | 0.82 | PIK3CA (0.35) | PIK3CAPIK3R1PRMT5WDR77CHEK1 | |
| SCHEMBL14161859 | 0.82 | PIK3CA (0.38) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4784163 | 0.82 | PIK3CA (0.35) | PIK3CAPIK3R1PRMT5WDR77CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |