Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16363146 | 0.84 | MAPT (0.42) | MAPTHSD11B1RECQLMEN1TSHR | |
| SCHEMBL13093073 | 0.75 | MAPT (0.38) | MAPTHSD11B1RECQLMEN1TSHR | |
| SCHEMBL13814459 | 0.71 | MAPT (0.50) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL13104703 | 0.70 | MAPT (0.38) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL16996979 | 0.70 | MAPT (0.38) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL23562435 | 0.70 | RECQL (0.39) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL1544451 | 0.70 | MAPT (0.49) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL4786220 | 0.69 | MAPT (0.37) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL11339077 | 0.69 | MAPT (0.37) | MAPTRECQLMEN1TSHRKMT2A | |
| SCHEMBL9334627 | 0.69 | MAPT (0.47) | MAPTRECQLMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303522-A1 | ARYLTETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF | NIHON NOHYAKU CO., LTD. (JP) | 2023-09-28 | — | — | US | disclosed |
| EP-4174057-A1 | ARYLTETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, INSECTICIDE COMPRISING SAID COMPOUND, AND METHOD FOR USING SAID INSECTICIDE | Nihon Nohyaku Co., Ltd. (JP) | 2023-05-03 | — | — | EP | disclosed |
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| WO-2021261563-A1 | ARYLTETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, INSECTICIDE COMPRISING SAID COMPOUND, AND METHOD FOR USING SAID INSECTICIDE | 日本農薬株式会社 | 2021-12-30 | — | — | WO | disclosed |
| WO-2015117912-A1 | PESTICIDALLY ACTIVE AMIDE DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-13 | — | — | WO | disclosed |
| US-8247401-B2 | P2X3 receptor antagonists for treatment of pain | MERCK SHARP & DOHME CORP. (US) | 2012-08-21 | — | — | US | disclosed |
| US-7625888-B2 | Fused triazole derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20090151779-A1 | Redox Couples, Compositions and Uses Thereof | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| WO-2008074991-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008074991-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| US-20070231874-A1 | Crystal of glucokinase protein, and method for drug design using the crystal | KAMATA KENJI | 2007-10-04 | — | — | US | disclosed |
| US-20070231874-A1 | Crystal of glucokinase protein, and method for drug design using the crystal | KAMATA KENJI | 2007-10-04 | — | — | US | disclosed |
| US-20070208010-A1 | Fused Triazole Derivatives as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes | MERCK SHARP & DOHME CORP. | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208010-A1 | Fused Triazole Derivatives as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes | DPP4, DPP3, DPP7 | MAPT 3004/4885HSD11B1 356/4885RECQL 2168/4885 |
| US-20230303522-A1 | ARYLTETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF | CYP4Z1, DDT, AADAC | MAPT 3522/4885HSD11B1 79/4885RECQL 3215/4885 |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | ALK, DPYD, DDT | MAPT 3291/4885HSD11B1 4136/4885RECQL 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.