Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785962 | 1.00 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL4785966 | 1.00 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL1751967 | 0.93 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL1750971 | 0.87 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL1751845 | 0.87 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL1751843 | 0.87 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL1750969 | 0.87 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL1752181 | 0.83 | REN (0.70) | RENCYP3A4 | |
| SCHEMBL1751089 | 0.83 | REN (0.49) | RENCYP3A4 | |
| SCHEMBL5455029 | 0.82 | REN (0.47) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981847-A1 | SECONDARY AMINES AS RENIN INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007088514-A1 | SECONDARY AMINES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-09 | — | — | WO | disclosed |