Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.43 |
| ▸ | PPARA | Q07869 | 16/20 | 0.43 |
| ▸ | PPARG | P37231 | 11/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146342 | 0.91 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL4741580 | 0.84 | PPARA (0.56) | PPARDPPARAPPARG | |
| SCHEMBL4739607 | 0.83 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL217887 | 0.81 | KDM4E (0.44) | PPARDPPARAPPARG | |
| SCHEMBL4737604 | 0.81 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL14146852 | 0.79 | PPARA (0.52) | PPARDPPARAPPARG | |
| SCHEMBL14146844 | 0.78 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL217859 | 0.78 | PPARA (0.39) | PPARDPPARAPPARG | |
| SCHEMBL4739629 | 0.77 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL219974 | 0.77 | PPARD (0.43) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |