Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.45 |
| ▸ | PPARA | Q07869 | 14/20 | 0.41 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217859 | 0.83 | PPARA (0.39) | PPARDPPARAPPARG | |
| SCHEMBL217887 | 0.83 | KDM4E (0.44) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL219974 | 0.82 | PPARD (0.43) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL4785998 | 0.81 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL4741580 | 0.81 | PPARA (0.56) | PPARDPPARAPPARGALDH1A1 | |
| SCHEMBL4736807 | 0.80 | PTGDR2 (0.43) | PPARDPPARAPPARGMMP1PTGDR2 | |
| SCHEMBL4739629 | 0.79 | PPARA (0.51) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL4736815 | 0.78 | MRGPRX4 (0.35) | PPARDPPARAPPARGPTGDR2ALDH1A1 | |
| SCHEMBL4737420 | 0.77 | MMP1 (0.48) | MMP1ALDH1A1MAPTPTPN1 | |
| SCHEMBL219071 | 0.77 | HSD17B2 (0.41) | PPARDPPARAPPARGPTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |