SCHEMBL4786009

SCHEMBL4786009

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)CCCO.Cc1ccc(C(=O)N2CCC(c3ccc(C(=O)N(C)C)cc3)CC2)cc1NS(=O)(=O)Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4183664 0.90 FASN (0.60) FASN
SCHEMBL4176902 0.90 FASN (0.59) FASN
SCHEMBL4183465 0.90 FASN (0.45) FASN
SCHEMBL4175554 0.86 FASN (0.58) FASN
SCHEMBL4174408 0.85 FASN (0.59) FASN
SCHEMBL4184050 0.85 FASN (0.62) FASN
SCHEMBL4181937 0.83 FASN (0.62) FASN
SCHEMBL4186633 0.83 FASN (0.62) FASN
SCHEMBL4180433 0.83 FASN (0.59) FASN
SCHEMBL4175739 0.82 FASN (0.57) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075070-A1 SULFONAMIDE DERIVATIVES FOR THERAPEUTIC USE AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-06-26 WO disclosed