Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786912 | 0.96 | KDR (0.54) | EPHX1KDRHTTMEN1GAA | |
| SCHEMBL4786463 | 0.89 | KDR (0.56) | EPHX1KDRHTTMEN1GAA | |
| SCHEMBL4787476 | 0.89 | EPHX1 (0.52) | EPHX1KDRHTTMAPTKMT2A | |
| SCHEMBL4785993 | 0.88 | EPHX1 (0.53) | EPHX1KDRHTTMAPTEPHX2 | |
| SCHEMBL4787348 | 0.88 | EPHX2 (0.55) | EPHX1KDRHTTMAPTEPHX2 | |
| SCHEMBL4687419 | 0.87 | MEN1 (0.56) | EPHX1KDRHTTMEN1GAA | |
| SCHEMBL4787668 | 0.87 | MAPT (0.51) | EPHX1KDRHTTMAPTEPHX2 | |
| SCHEMBL4783970 | 0.87 | EPHX2 (0.60) | EPHX1HTTMEN1KMT2AEPHX2 | |
| SCHEMBL5149417 | 0.87 | EPHX1 (0.52) | EPHX1KDRHTTKMT2AEPHX2 | |
| SCHEMBL4787105 | 0.87 | EPHX1 (0.52) | EPHX1KDRHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |