Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786912 | 0.94 | KDR (0.54) | KDREPHX1HTTALDH1A1MEN1 | |
| SCHEMBL4786099 | 0.89 | EPHX1 (0.52) | KDREPHX1HTTALDH1A1MEN1 | |
| SCHEMBL4786969 | 0.88 | EPHX2 (0.52) | KDREPHX1HTTALDH1A1MAPT | |
| SCHEMBL4683734 | 0.87 | KDR (0.56) | KDREPHX1HTTALDH1A1MEN1 | |
| SCHEMBL5149857 | 0.87 | KDR (0.56) | KDREPHX1HTTALDH1A1MEN1 | |
| SCHEMBL4683716 | 0.87 | KDR (0.56) | KDREPHX1HTTALDH1A1MEN1 | |
| SCHEMBL5184123 | 0.86 | PKM (0.53) | KDREPHX1HTTALDH1A1KMT2A | |
| SCHEMBL4799886 | 0.86 | KDR (0.47) | KDREPHX1HTTALDH1A1KMT2A | |
| SCHEMBL4786779 | 0.85 | EPHX2 (0.52) | KDREPHX1HTTALDH1A1MEN1 | |
| SCHEMBL4687419 | 0.85 | MEN1 (0.56) | KDREPHX1HTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |