Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 12/20 | 0.51 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.51 |
| ▸ | INPP5B | P32019 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12005085 | 0.74 | SRC (0.67) | INPPL1INPP5AINPP5BSRCGPR84 | |
| SCHEMBL130697 | 0.73 | INPPL1 (0.71) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL4186925 | 0.73 | INPPL1 (0.71) | INPPL1INPP5AINPP5BAKT1SRC | |
| Biphenyl SCHEMBL18000012 | 0.72 | SRC (0.69) | INPPL1INPP5AINPP5BSRCKDM4E | |
| Biphenyl SCHEMBL2780711 | 0.72 | SRC (0.69) | INPPL1INPP5AINPP5BSRCKDM4E | |
| Phosphoric Acid SCHEMBL28992406 | 0.71 | INPPL1 (0.68) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL10438537 | 0.70 | INPPL1 (0.47) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL3727874 | 0.69 | INPPL1 (1.00) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL7747354 | 0.69 | SRC (0.58) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL28608140 | 0.68 | SRC (0.45) | INPPL1INPP5AINPP5BAKT1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064244-A9 | PHOSPHOINOSITIDE MODULATION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV COLUMBIA (US) | 2008-08-21 | — | — | WO | claimed |
| WO-2008064244-A2 | PHOSPHOINOSITIDE MODULATION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-05-29 | — | — | WO | claimed |