Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | STS | P08842 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713102 | 0.89 | STS (0.53) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL17398495 | 0.89 | ESR2 (0.52) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL14401199 | 0.89 | STS (0.53) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL23291499 | 0.88 | STS (0.50) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL24629830 | 0.88 | STS (0.50) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL29535159 | 0.88 | STS (0.50) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL23535949 | 0.88 | GPR119 (0.56) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL4334254 | 0.87 | MAPT (0.56) | CNR1STSMAPTKDM4ETHRB | |
| SCHEMBL8223129 | 0.86 | MEN1 (0.60) | STSMAPTKDM4ETHRBMEN1 | |
| SCHEMBL12713099 | 0.86 | MEN1 (0.52) | CNR1STSMAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |