Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4787381 | 0.99 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL4786548 | 0.88 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1 | |
| SCHEMBL1866718 | 0.86 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL4784916 | 0.85 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL4784799 | 0.84 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1 | |
| SCHEMBL1863833 | 0.83 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL1305085 | 0.81 | HSP90AA1 (0.70) | HSP90AA1HSP90AB1 | |
| SCHEMBL3709121 | 0.81 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL1861236 | 0.81 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL12368058 | 0.80 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103353-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2008-08-28 | — | — | WO | claimed |
| WO-2008103353-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2008-08-28 | — | — | WO | disclosed |