Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 16/20 | 0.72 |
| ▸ | CTSK | P43235 | 15/20 | 0.72 |
| ▸ | CTSS | P25774 | 14/20 | 0.72 |
| ▸ | CTSB | P07858 | 10/20 | 0.72 |
| ▸ | GRN | P28799 | 1/20 | 0.64 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.64 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085485 | 1.00 | CTSL (0.72) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL1169219 | 1.00 | CTSL (0.72) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL1169217 | 1.00 | CTSL (0.72) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL4085479 | 1.00 | CTSL (0.72) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL2156284 | 0.90 | CTSL (0.60) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL3769248 | 0.87 | CTSL (0.56) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL13624191 | 0.87 | CTSL (0.71) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL14579994 | 0.87 | CTSL (0.70) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL2154979 | 0.87 | CTSL (0.70) | CTSLCTSKCTSSCTSBGRN | |
| SCHEMBL13624187 | 0.87 | CTSL (0.70) | CTSLCTSKCTSSCTSBGRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899336-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007006716-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |