Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741186 | 0.92 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL4787929 | 0.91 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL4787352 | 0.90 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL4739900 | 0.90 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL1398783 | 0.86 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL4738226 | 0.85 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL4741194 | 0.84 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL4742498 | 0.84 | HCRTR1 (0.51) | HCRTR1HCRTR2NR1I3 | |
| SCHEMBL4786332 | 0.83 | HCRTR1 (0.51) | HCRTR1HCRTR2NR1I3 | |
| SCHEMBL1398568 | 0.81 | HCRTR1 (0.67) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087611-A2 | PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-24 | — | — | WO | disclosed |