Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464151 | 0.85 | MEN1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL29942640 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MEN1KMT2AIDO1 | |
| SCHEMBL10840406 | 0.79 | IDO1 (0.52) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5084514 | 0.76 | CNR2 (0.57) | MEN1KMT2AHTTIDO1MAOB | |
| SCHEMBL4023321 | 0.76 | MEN1 (0.49) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL10987489 | 0.76 | MAOB (0.50) | ALDH1A1MEN1KMT2AHTTIDO1 | |
| SCHEMBL10973695 | 0.76 | KMT2A (0.49) | ALDH1A1MEN1KMT2AHTTIDO1 | |
| SCHEMBL25035900 | 0.73 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL1456362 | 0.72 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL31607672 | 0.72 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069500-A1 | TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |