Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.64 |
| ▸ | TP53 | P04637 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8276253 | 1.00 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4956379 | 0.99 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4787881 | 0.99 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4958803 | 0.99 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL14061740 | 0.82 | NR1H4 (0.47) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL14153292 | 0.82 | SMN1; SMN2 (0.54) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8274898 | 0.81 | NR1H4 (0.74) | RAB9ANPC1ALDH1A1NR1H4CYP1A2 | |
| SCHEMBL8276225 | 0.81 | NR1H4 (0.74) | RAB9ANPC1ALDH1A1NR1H4CYP1A2 | |
| SCHEMBL15848298 | 0.81 | NR1H4 (0.74) | RAB9ANPC1ALDH1A1NR1H4CYP1A2 | |
| Hydrochloric Acid SCHEMBL4955787 | 0.80 | NR1H4 (0.72) | RAB9ANPC1ALDH1A1NR1H4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093960-A1 | NOVEL DIPEPTIDYL PEPTIDASE-IV INHIBITORS | LG LIFE SCIENCES, LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |
| US-20080015146-A1 | Dpp-IV Inhibitors | SANTHERA PHARMACEUTICALS (DEUTSCHLAND) AG (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015146-A1 | Dpp-IV Inhibitors | SANTHERA PHARMACEUTICALS (DEUTSCHLAND) AG (DE) | 2008-01-17 | — | — | US | disclosed |
| WO-2005121131-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015146-A1 | Dpp-IV Inhibitors | DPP4, DPP9, DPP3 | RAB9A 218/4885NPC1 1084/4885SMN1; SMN2 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.