Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788712 | 0.91 | LMNA (0.49) | GAAKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4753150 | 0.73 | GAA (0.45) | GAAPRMT5WDR77 | |
| SCHEMBL4750479 | 0.73 | MAPT (0.56) | GAAKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4788651 | 0.72 | GAA (0.57) | GAAKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4788366 | 0.71 | GAA (0.78) | GAAKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4788931 | 0.70 | GAA (0.53) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7854831 | 0.70 | LMNA (0.58) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7861680 | 0.68 | TSHR (0.73) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7854934 | 0.66 | LMNA (0.67) | GAAKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4787601 | 0.66 | OPRL1 (0.59) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |