Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714145 | 0.87 | CETP (0.57) | CETPMAPTL3MBTL1EEDLMNA | |
| SCHEMBL20361203 | 0.83 | MAPT (0.45) | CETPMAPTL3MBTL1NAPEPLDHTT | |
| SCHEMBL1123836 | 0.82 | NAPEPLD (0.62) | CETPMAPTNAPEPLDEEDHTT | |
| SCHEMBL1124012 | 0.80 | TSHR (0.49) | CETPMAPTNAPEPLDEEDPOLB | |
| SCHEMBL1123909 | 0.80 | GRIN2D (0.48) | CETPNAPEPLDEEDPOLBKDM4E | |
| SCHEMBL1124032 | 0.78 | TSHR (0.51) | CETPMAPTNAPEPLDEEDHTT | |
| SCHEMBL1308905 | 0.78 | MAPT (0.61) | MAPTL3MBTL1HTTPOLBLMNA | |
| SCHEMBL15334821 | 0.76 | CETP (0.59) | CETPNAPEPLDHTTPOLBKMT2A | |
| SCHEMBL1123980 | 0.76 | HRH4 (0.67) | CETPNAPEPLDHTTKMT2ANPSR1 | |
| SCHEMBL3241588 | 0.75 | CETP (0.49) | CETPEEDHTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |