Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | PRKCG | P05129 | 3/20 | 0.43 |
| ▸ | PRKCB | P05771 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | PRKCH | P24723 | 3/20 | 0.43 |
| ▸ | PRKCI | P41743 | 3/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200004 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL4786361 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL8912364 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL5172075 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL4786370 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL11157696 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL11159944 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL11198963 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL6069252 | 0.98 | USP2 (0.42) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL5170197 | 0.91 | USP2 (0.39) | USP2CES2GMNNPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249066-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080249066-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080249066-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-09 | — | — | US | disclosed |
| WO-2008118879-A2 | ANTIVIRAL COMPOSITIONS COMPRISING 2 COMPOUNDS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008118879-A2 | ANTIVIRAL COMPOSITIONS COMPRISING 2 COMPOUNDS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249066-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS | PNP, TYMP, MTAP | USP2 4155/4885CES2 293/4885GMNN 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.