Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | PRKCG | P05129 | 3/20 | 0.43 |
| ▸ | PRKCB | P05771 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | PRKCH | P24723 | 3/20 | 0.43 |
| ▸ | PRKCI | P41743 | 3/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200004 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL4786361 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL5172075 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL4786647 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL4786370 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL11157696 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL11159944 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL11198963 | 1.00 | USP2 (0.46) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL6069252 | 0.98 | USP2 (0.42) | USP2CES2GMNNPOLBBLM | |
| SCHEMBL5170197 | 0.91 | USP2 (0.39) | USP2CES2GMNNPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614548-A | TREATING TUMORS AND HIV INFECTION, PROTEIN KINASE C INHIBITORS | WAKE FOREST UNIVERSITY (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1990004918-A2 | QUATERNARY AMINE CONTAINING ETHER OR ESTER LIPID DERIVATIVES AND THERAPEUTIC COMPOSITIONS | WAKE FOREST UNIVERSITY (US) | 1990-05-17 | — | — | WO | disclosed |
| US-4622392-A | ANTICARCINOGENIC AGENTS | HEALTH RESEARCH INC. (ROSWELL PARK DIVISION) (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0118090-B1 | NEW 3-ALKYLTHIO-2-O-CARBAMOYL-PROPANE-1.2-DIOL-1-O-PHOSPHOCHOLINES, AND PROCESSES FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1986-11-05 | — | — | EP | disclosed |
| EP-0183843-A1 | THIOPHOSPHOLIPID CONJUGATES OF ANTITUMOR AGENTS | HEALTH RESEARCH, INC. (US) | 1986-06-11 | — | — | EP | disclosed |
| WO-1986000309-A1 | THIOPHOSPHOLIPID CONJUGATES OF ANTITUMOR AGENTS | HEALTH RESEARCH INC. (US) | 1986-01-16 | — | — | WO | disclosed |
| EP-0118090-A1 | New 3-alkylthio-2-O-carbamoyl-propane-1.2-diol-1-O-phosphocholines, and processes for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-09-12 | — | — | EP | disclosed |
| EP-0043472-B1 | 3-HYDROCARBYLTHIO-2-ACYLOXYPROPYL 2-TRIMETHYLAMMONIOETHYL PHOSPHATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1983-07-20 | — | — | EP | disclosed |