Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787261 | 0.93 | KDR (0.52) | EPHX1KDRKMT2APNLIPEPHX2 | |
| SCHEMBL4787221 | 0.90 | EPHX1 (0.52) | EPHX1KDRKMT2APNLIPEPHX2 | |
| SCHEMBL4788099 | 0.87 | KDR (0.50) | EPHX1KDRKMT2APNLIPEPHX2 | |
| SCHEMBL4784915 | 0.86 | EPHX1 (0.54) | EPHX1KDRKMT2AEPHX2ALDH1A1 | |
| SCHEMBL4787476 | 0.85 | EPHX1 (0.52) | EPHX1KDRKMT2AEPHX2TBXA2R | |
| SCHEMBL4238811 | 0.84 | PKM (0.50) | KMT2APNLIPMCHR1PTPN1TP53 | |
| SCHEMBL4682919 | 0.84 | HDAC1 (0.51) | EPHX1KDRKMT2AEPHX2TBXA2R | |
| SCHEMBL4787374 | 0.83 | KDR (0.54) | EPHX1KDRKMT2AEPHX2ALDH1A1 | |
| SCHEMBL4787754 | 0.82 | TBXA2R (0.62) | EPHX1KMT2ATBXA2R | |
| SCHEMBL4787668 | 0.82 | MAPT (0.51) | EPHX1KDRPNLIPEPHX2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |