Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814491 | 0.85 | MEN1 (0.43) | KDM4EALDH1A1EGLN3TP53KMT2A | |
| SCHEMBL27756022 | 0.81 | KDM4E (0.36) | KDM4EHTTALDH1A1EGLN3HSD17B10 | |
| SCHEMBL11011551 | 0.81 | HPGD (0.47) | KDM4EHTTALDH1A1 | |
| SCHEMBL3961900 | 0.81 | ALDH1A1 (0.37) | KDM4EHTTALDH1A1EGLN3 | |
| SCHEMBL1906544 | 0.78 | — | — | |
| SCHEMBL11067549 | 0.77 | ALDH1A1 (0.39) | HTTALDH1A1EGLN3NFKB1QPCT | |
| SCHEMBL10662530 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2A | |
| SCHEMBL27427200 | 0.76 | HTT (0.41) | KDM4EHTTALDH1A1EGLN3NFKB1 | |
| Hydrochloric Acid SCHEMBL28307730 | 0.76 | CYP3A4 (0.37) | HTTALDH1A1EGLN3NFKB1QPCT | |
| SCHEMBL9113432 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099165-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | WO | disclosed |