Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203599 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL8372651 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL8215173 | 0.80 | MCL1 (0.46) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL7668304 | 0.79 | MEN1 (0.59) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL7660492 | 0.79 | MEN1 (0.42) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL7667988 | 0.77 | MEN1 (0.43) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL11142234 | 0.76 | AKR1C3 (0.36) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL7659272 | 0.76 | KMT2A (0.46) | ALDH1A1AKR1C3MEN1KMT2ARECQL | |
| SCHEMBL7978970 | 0.75 | MEN1 (0.42) | ALDH1A1TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL7666081 | 0.74 | MEN1 (0.41) | ALDH1A1TSHRAKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128038-A2 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-10-23 | — | — | WO | claimed |