SCHEMBL4786934

SCHEMBL4786934

NC(=O)C(=O)NC(O)=S.NC(O)=S

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAS2R38 P59533 1/20 0.36
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
TGFBR1 P36897 1/20 0.33
ALDH1A1 P00352 1/20 0.32
KDM5B Q9UGL1 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28777789 0.74 CRBN (0.41) TAS2R38LDHALDHBALDH1A1ACHE
SCHEMBL5838429 0.73
SCHEMBL1913679 0.73
SCHEMBL9634223 0.73
SCHEMBL4786929 0.72
SCHEMBL23002894 0.71
Hydrogen Sulfide SCHEMBL10563693 0.71 KDM5B (0.59) KDM5B
SCHEMBL20971436 0.71 CRBN (0.43) TAS2R38LDHALDHBALDH1A1ACHE
SCHEMBL9418208 0.70 ALDH1A1 (0.38) TAS2R38ALDH1A1ACHE
SCHEMBL28740940 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008092945-A1 ORGANIC MOLYBDENUM COMPOUNDS AND LUBRICATING COMPOSITIONS COMPRISING SAID COMPOUNDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-08-07 WO disclosed