Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | BCR | P11274 | 3/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14103922 | 0.88 | HPGD (0.55) | HPGDABL1BCRCYP11B2CYP11B1 | |
| SCHEMBL4785416 | 0.86 | KMT2A (0.59) | HPGDCA1CA2CA7CA9 | |
| SCHEMBL4785886 | 0.81 | HPGD (0.57) | HPGDCYP11B2CYP11B1CA1CA2 | |
| SCHEMBL14925159 | 0.79 | HPGD (0.63) | HPGDCA1CA2CA7CA9 | |
| SCHEMBL14916667 | 0.79 | HPGD (0.63) | HPGDCA1CA2CA7CA9 | |
| SCHEMBL14103595 | 0.76 | KMT2A (0.52) | HPGDCA1CA2CA7CA9 | |
| SCHEMBL4783634 | 0.76 | CYP1A2 (0.54) | HPGDKMT2AMEN1ROCK2ALDH1A1 | |
| SCHEMBL23856224 | 0.75 | HPGD (0.69) | HPGDKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL30062682 | 0.75 | HPGD (0.69) | HPGDKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL13943084 | 0.74 | CDK4 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095852-A1 | BRONCHORELAXING ARYLAMIDES | RESPIRATORIUS AB (SE) | 2008-08-14 | — | — | WO | disclosed |