Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738640 | 0.86 | KMT2A (0.76) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4785416 | 0.85 | KMT2A (0.59) | HPGDSMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL14103923 | 0.83 | HPGD (0.55) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4787071 | 0.81 | HPGD (0.58) | HPGDSMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL10530895 | 0.77 | ALDH1A1 (0.56) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14103595 | 0.76 | KMT2A (0.52) | HPGDSMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL4739367 | 0.74 | CA1 (0.62) | HPGDHTTMEN1KMT2ACA1 | |
| SCHEMBL29598514 | 0.74 | STAT3 (0.68) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27197578 | 0.74 | STAT3 (0.68) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14925159 | 0.74 | HPGD (0.63) | HPGDHTTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095852-A1 | BRONCHORELAXING ARYLAMIDES | RESPIRATORIUS AB (SE) | 2008-08-14 | — | — | WO | disclosed |