Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 10/20 | 0.85 |
| ▸ | UBA2 | Q9UBT2 | 10/20 | 0.85 |
| ▸ | MEN1 | O00255 | 8/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.85 |
| ▸ | CASP1 | P29466 | 7/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.85 |
| ▸ | BLM | P54132 | 5/20 | 0.85 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | RECQL | P46063 | 4/20 | 0.85 |
| ▸ | POLB | P06746 | 4/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.85 |
| ▸ | CASP6 | P55212 | 3/20 | 0.85 |
| ▸ | NSD2 | O96028 | 2/20 | 0.85 |
| ▸ | TP53 | P04637 | 2/20 | 0.85 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.85 |
| ▸ | HBB | P68871 | 2/20 | 0.85 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787869 | 0.92 | SAE1 (1.00) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL15256873 | 0.91 | SAE1 (0.87) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL15256912 | 0.91 | SAE1 (1.00) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL4787545 | 0.91 | SAE1 (1.00) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL4787907 | 0.88 | SAE1 (0.94) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL6980462 | 0.87 | SAE1 (1.00) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL8163982 | 0.85 | SAE1 (0.62) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL15256907 | 0.85 | SAE1 (1.00) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL15256865 | 0.83 | SAE1 (0.86) | SAE1UBA2MEN1KMT2AKDM4E | |
| SCHEMBL15256874 | 0.83 | SAE1 (1.00) | SAE1UBA2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| US-20250354117-A1 | METHODS OF GENERATING NATURAL KILLER CELLS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF | CHILDRENS MEDICAL CT CORP (US) | 2025-11-20 | — | — | US | disclosed |
| WO-2023225629-A2 | METHODS OF GENERATING NATURAL KILLER CELLS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-11-23 | — | — | WO | disclosed |