Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 11/20 | 0.94 |
| ▸ | UBA2 | Q9UBT2 | 11/20 | 0.94 |
| ▸ | CASP1 | P29466 | 7/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.94 |
| ▸ | MEN1 | O00255 | 7/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.81 |
| ▸ | BLM | P54132 | 5/20 | 0.81 |
| ▸ | POLB | P06746 | 5/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | RECQL | P46063 | 3/20 | 0.81 |
| ▸ | NSD2 | O96028 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 2/20 | 0.81 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.81 |
| ▸ | CASP6 | P55212 | 2/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | HBB | P68871 | 2/20 | 0.81 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787545 | 0.97 | SAE1 (1.00) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL4787869 | 0.89 | SAE1 (1.00) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL15256873 | 0.89 | SAE1 (0.87) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL4787152 | 0.88 | SAE1 (0.85) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL8156489 | 0.86 | SAE1 (0.70) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL8161071 | 0.83 | SAE1 (0.75) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL15256907 | 0.82 | SAE1 (1.00) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL15032610 | 0.81 | SAE1 (0.72) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL15256865 | 0.80 | SAE1 (0.86) | SAE1UBA2CASP1HSD17B10ALOX15 | |
| SCHEMBL15256874 | 0.80 | SAE1 (1.00) | SAE1UBA2CASP1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |