Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785276 | 0.91 | KDR (0.50) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4787374 | 0.88 | KDR (0.54) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4787261 | 0.87 | KDR (0.52) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4689117 | 0.86 | CYP1A2 (0.57) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4788099 | 0.85 | KDR (0.50) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4228580 | 0.85 | PKM (0.51) | PKMMEN1GAAMAPTHTT | |
| SCHEMBL4786912 | 0.84 | KDR (0.54) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4683734 | 0.84 | KDR (0.56) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL4683716 | 0.84 | KDR (0.56) | KDREPHX1PKMHSD17B10MEN1 | |
| SCHEMBL5149857 | 0.84 | KDR (0.56) | KDREPHX1PKMHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |