Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788212 | 0.85 | ADORA1 (0.52) | ADORA1SMN1; SMN2LMNAATMPABPC1 | |
| SCHEMBL2078683 | 0.79 | LMNA (0.62) | ADORA1SMN1; SMN2LMNAATMPABPC1 | |
| SCHEMBL4761427 | 0.78 | ADORA1 (0.51) | ADORA1SMN1; SMN2LMNAATMPABPC1 | |
| SCHEMBL976854 | 0.76 | ADORA1 (0.48) | ADORA1SMN1; SMN2LMNAATMPABPC1 | |
| SCHEMBL27302179 | 0.75 | ADORA1 (0.81) | ADORA1SMN1; SMN2LMNAATMGAA | |
| SCHEMBL938730 | 0.75 | ADORA1 (0.84) | ADORA1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL16328025 | 0.74 | ADORA1 (0.56) | ADORA1SMN1; SMN2LMNAATMGAA | |
| SCHEMBL21005765 | 0.74 | ADORA1 (0.56) | ADORA1SMN1; SMN2LMNAATMGAA | |
| SCHEMBL6868401 | 0.74 | ADORA1 (0.56) | ADORA1SMN1; SMN2LMNAATMGAA | |
| SCHEMBL22029691 | 0.74 | ADORA1 (0.51) | ADORA1SMN1; SMN2LMNAATMPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134354-A1 | TNF-α PRODUCTION INHIBITOR | ARRAY BIOPHARMA, INC. (US) | 2008-11-06 | — | — | WO | disclosed |