Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918364 | 0.96 | SCN4A (0.52) | SCN4AAKT1ALDH1A1PARP1AKT2 | |
| Hydrochloric Acid SCHEMBL30014721 | 0.94 | SCN4A (0.50) | SCN4AAKT1ALDH1A1PARP1AKT2 | |
| SCHEMBL5070318 | 0.81 | KDR (0.41) | ALDH1A1PARP1USP2MAPTLMNA | |
| SCHEMBL17151369 | 0.81 | SCN4A (0.46) | SCN4ARAB9APIM1GSK3BCLK4 | |
| SCHEMBL2473305 | 0.81 | KMT2A (0.42) | NPC1RAB9AALDH1A1PARP1KDM4E | |
| SCHEMBL28815828 | 0.81 | RPS6KA3 (0.47) | RPS6KA3PIM1CDK2GSK3B | |
| SCHEMBL11094847 | 0.80 | PDPK1 (0.52) | SMN1; SMN2AKT1ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29878808 | 0.79 | RPS6KA3 (0.46) | RPS6KA3PIM1CDK2GSK3B | |
| Hydrochloric Acid SCHEMBL30015576 | 0.79 | SCN4A (0.45) | SCN4ARAB9APIM1GSK3BCLK4 | |
| SCHEMBL1456892 | 0.79 | HCAR2 (0.41) | SCN4AALDH1A1PARP1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503591-B | Pyridazinone derivative, method for producing same, and organic electroluminescent element | 上海和辉光电有限公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-2001885-A2 | OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES | Abbott Laboratories (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007100990-A2 | OCTAHYDRO-PYRROLO[3,4-B] PYRROLE DERIVATIVES AND THEIR USE AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2007-09-07 | — | — | WO | disclosed |