SCHEMBL918364

SCHEMBL918364

O=c1[nH]nccc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 1/20 0.52
AKT1 P31749 2/20 0.42
PARP1 P09874 1/20 0.42
AKT2 P31751 1/20 0.42
LMNA P02545 1/20 0.42
AKT3 Q9Y243 2/20 0.42
RPS6KA3 P51812 2/20 0.42
AURKA O14965 1/20 0.42
CDK1 P06493 1/20 0.42
LYN P07948 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
PRKACA P17612 1/20 0.42
RPS6KB1 P23443 1/20 0.42
CDK2 P24941 1/20 0.42
MARK3 P27448 1/20 0.42
GSK3B P49841 1/20 0.42
PRKCZ Q05513 1/20 0.42
PRKCD Q05655 1/20 0.42
ERBB4 Q15303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30014721 0.98 SCN4A (0.50) SCN4AAKT1PARP1AKT2LMNA
SCHEMBL4787445 0.96 SCN4A (0.48) SCN4AAKT1PARP1AKT2LMNA
SCHEMBL11094847 0.83 PDPK1 (0.52) AKT1LMNAAKT3RPS6KA3AURKA
SCHEMBL1456892 0.82 HCAR2 (0.41) SCN4APARP1LMNAPIM1ALDH1A1
SCHEMBL14955294 0.81 CYP2A6 (0.58) LMNAAURKAPIM1GSK3BHPGDS
SCHEMBL17151369 0.80 SCN4A (0.46) SCN4APIM1GSK3BTGFBR1BTK
SCHEMBL2473305 0.80 KMT2A (0.42) PARP1LMNAHPGDSALDH1A1BTK
SCHEMBL28815828 0.80 RPS6KA3 (0.47) RPS6KA3PIM1CDK2GSK3B
SCHEMBL5070318 0.80 KDR (0.41) PARP1LMNAPRKACAALDH1A1MAPT
SCHEMBL28051817 0.80 NOTUM (0.62) NOTUMLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4371986-B1 SUBSTITUTED PYRIDAZINONES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-12540120-B2 Herbicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2026-02-03 US claimed
US-12540128-B2 Substituted pyridazinones as herbicides SYNGENTA CROP PROTECTION AG (CH) 2026-02-03 US claimed
US-12162840-B2 Herbicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2024-12-10 US claimed
CN-114555563-B Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-11-15 CN claimed
EP-3999494-B1 SUBSTITUTED PYRIDAZINONES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-09-11 EP claimed
CN-114144409-B Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-08-09 CN claimed
EP-3890487-B1 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2024-06-12 EP claimed
CN-118108674-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-31 CN claimed
CN-118084802-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN claimed
EP-1070055-A1 SUBSTITUTED PHENYL PYRIDAZINONES Bayer Aktiengesellschaft (DE) 2001-01-24 EP claimed
US-6063781-A MITICIDES, INSECTICIDES AND NEMATOCIDES CROMPTON CO./CIE (CA) 2000-05-16 US claimed
WO-1999052878-A1 SUBSTITUTED PHENYL PYRIDAZINONES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO claimed
CN-1192208-A Phenylpyridazinones BAYER AG (DE) 1998-09-02 CN claimed
EP-0832072-A1 PHENYLPYRIDAZINONES BAYER AG (DE) 1998-04-01 EP claimed
WO-1996039392-A1 PHENYLPYRIDAZINONES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-12 WO claimed
EP-0401219-A1 COMPOSITION CONTAINING PHENYLPYRIDAZINONE DERIVATIVES FOR PROMOTING GROWTH AND REDUCING FAT IN ANIMALS BASF Aktiengesellschaft (DE) 1990-12-12 EP claimed
WO-1989003181-A1 COMPOSITION CONTAINING PHENYLPYRIDAZINONE DERIVATIVES FOR PROMOTING GROWTH AND REDUCING FAT IN ANIMALS BASF AKTIENGESELLSCHAFT (DE) 1989-04-20 WO claimed
WO-1987006428-A1 PESTICIDAL CONCENTRATE COMPOSITIONS KEMISK VA^ERK KO^/GE A/S (DK) 1987-11-05 WO claimed
EP-0243872-A1 Pesticidal concentrate compositions BEROL NOBEL (SUISSE) S.A. (CH) 1987-11-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540128-B2 Substituted pyridazinones as herbicides CBR3, CBR1, CNPY2 SCN4A 1007/4885AKT1 3519/4885PARP1 3307/4885
US-12162840-B2 Herbicidal compositions DDT, HPD, PNPO SCN4A 4320/4885AKT1 4047/4885PARP1 2633/4885
US-12540120-B2 Herbicidal compounds CBR3, CBR1, HACL2 SCN4A 1184/4885AKT1 3030/4885PARP1 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.