Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 12/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787488 | 0.96 | TBXA2R (0.61) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4787754 | 0.92 | TBXA2R (0.62) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4787491 | 0.90 | TBXA2R (0.62) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4785961 | 0.89 | TBXA2R (0.59) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4785177 | 0.89 | TBXA2R (0.57) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5183248 | 0.88 | TBXA2R (0.56) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4786978 | 0.88 | TBXA2R (0.56) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4787919 | 0.87 | TBXA2R (0.56) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4786555 | 0.86 | TBXA2R (0.56) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4785959 | 0.86 | KMT2A (0.67) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |