Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787995 | 0.88 | TBXA2R (0.61) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4787051 | 0.87 | TBXA2R (0.62) | TBXA2RMEN1KMT2A | |
| SCHEMBL4785961 | 0.85 | TBXA2R (0.59) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4786650 | 0.85 | TBXA2R (0.61) | TBXA2RMEN1KMT2AMAPT | |
| SCHEMBL4787488 | 0.84 | TBXA2R (0.61) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4786779 | 0.84 | EPHX2 (0.52) | MEN1KMT2AMAPTPOLBEPHX2 | |
| SCHEMBL4683604 | 0.82 | MAPT (0.52) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL4235514 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL4684023 | 0.82 | MEN1 (0.60) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4684021 | 0.82 | MEN1 (0.60) | TBXA2RMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |