Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025711 | 0.90 | DRD2 (0.32) | TACR1SCN9A | |
| SCHEMBL4023240 | 0.88 | KDM2B (0.32) | MEN1KMT2ATACR1SCN9AMAPK1 | |
| SCHEMBL4749520 | 0.87 | SCN9A (0.32) | SCN9AKDM2B | |
| SCHEMBL4020878 | 0.86 | SCN9A (0.32) | SCN9AKDM2B | |
| SCHEMBL4022836 | 0.86 | BCHE (0.35) | MEN1KMT2ATACR1SCN9AMGLL | |
| SCHEMBL4028516 | 0.86 | BCHE (0.35) | MEN1KMT2ATACR1SCN9AMGLL | |
| SCHEMBL4022533 | 0.86 | BCHE (0.35) | MEN1KMT2ATACR1SCN9AMGLL | |
| SCHEMBL4028513 | 0.86 | BCHE (0.35) | MEN1KMT2ATACR1SCN9AMGLL | |
| SCHEMBL13721158 | 0.86 | BCHE (0.35) | MEN1KMT2ATACR1SCN9AMGLL | |
| SCHEMBL4028507 | 0.86 | BCHE (0.35) | MEN1KMT2ATACR1SCN9AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |