Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933881 | 0.84 | KDM4E (0.54) | PDE10AKDM4EHPGDALDH1A1CYP2C9 | |
| SCHEMBL14052589 | 0.82 | HPGD (0.46) | KDM4EHPGDALDH1A1ALOX15CYP2C9 | |
| SCHEMBL2018471 | 0.80 | FABP3 (0.47) | CDC25BPDE10AKDM4EHPGDALDH1A1 | |
| SCHEMBL976330 | 0.80 | KDM4E (0.57) | CDC25BPDE10AKDM4EHPGDALDH1A1 | |
| SCHEMBL18600627 | 0.80 | CDC25B (0.58) | CDC25BPDE10AKDM4EHPGDALDH1A1 | |
| SCHEMBL7813325 | 0.80 | PDE10A (0.51) | CDC25BPDE10AKDM4EHPGDALDH1A1 | |
| SCHEMBL15763605 | 0.79 | FOLH1 (0.51) | KDM4EALDH1A1MCL1L3MBTL1 | |
| SCHEMBL1010666 | 0.78 | ACMSD (0.46) | PDE10AKDM4EHPGDALDH1A1FABP3 | |
| SCHEMBL9933239 | 0.78 | PDE10A (0.49) | PDE10AKDM4EHPGDALDH1A1FABP3 | |
| SCHEMBL6638956 | 0.77 | KDM4E (0.53) | PDE10AKDM4EHPGDALDH1A1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | claimed |