Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 8/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787645 | 0.94 | TSHR (0.44) | TSHRSLC22A6LMNAPMP22NFKB1 | |
| SCHEMBL4788377 | 0.94 | TSHR (0.44) | TSHRSLC22A6LMNAPMP22NFKB1 | |
| SCHEMBL6343322 | 0.90 | LMNA (0.44) | TSHRSLC22A6LMNAALDH1A1APEX1 | |
| SCHEMBL6337538 | 0.90 | LMNA (0.44) | TSHRSLC22A6LMNAALDH1A1APEX1 | |
| SCHEMBL18620 | 0.75 | LMNA (0.61) | TSHRSLC22A6LMNAPMP22NFKB1 | |
| SCHEMBL6536625 | 0.75 | EPHX1 (0.45) | TSHRLMNAPMP22NFKB1ALDH1A1 | |
| SCHEMBL3858547 | 0.72 | LMNA (0.51) | LMNAALDH1A1THRB | |
| SCHEMBL58343 | 0.71 | LMNA (0.67) | TSHRSLC22A6LMNAPMP22NFKB1 | |
| SCHEMBL15864631 | 0.71 | TSHR (0.47) | TSHRSLC22A6LMNAPMP22NFKB1 | |
| SCHEMBL3504682 | 0.69 | LMNA (0.70) | TSHRSLC22A6LMNAPMP22NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122763-A1 | METHOD OF PEST AND FUNGAL CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2008-10-16 | — | — | WO | disclosed |