Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | RET | P07949 | 8/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546199 | 0.90 | GRM4 (0.52) | RETKDM4DPANK3GRM4CHRM4 | |
| SCHEMBL26582234 | 0.90 | GRM4 (0.52) | RETKDM4DPANK3GRM4CHRM4 | |
| SCHEMBL952010 | 0.84 | JAK3 (0.58) | DPP4RETKDM4DJAK3BTK | |
| SCHEMBL7078845 | 0.83 | RET (0.57) | DPP4RETKDM4DPANK3CHRM4 | |
| SCHEMBL5516092 | 0.83 | ACACB (0.45) | RETPANK3CHRM4JAK3BTK | |
| SCHEMBL29921126 | 0.83 | ACACB (0.45) | RETPANK3CHRM4JAK3BTK | |
| SCHEMBL22795648 | 0.83 | ACACB (0.45) | RETPANK3CHRM4JAK3BTK | |
| SCHEMBL22795726 | 0.83 | ACACB (0.45) | RETPANK3CHRM4JAK3BTK | |
| SCHEMBL5738130 | 0.83 | ACACB (0.45) | RETPANK3CHRM4JAK3BTK | |
| SCHEMBL31286029 | 0.83 | ACACB (0.45) | RETPANK3CHRM4JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |