Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 5/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29921126 | 1.00 | ACACB (0.45) | ACACBRETCPB2PPARGPPARD | |
| SCHEMBL22795648 | 1.00 | ACACB (0.45) | ACACBRETCPB2PPARGPPARD | |
| SCHEMBL22795726 | 1.00 | ACACB (0.45) | ACACBRETCPB2PPARGPPARD | |
| SCHEMBL5516092 | 1.00 | ACACB (0.45) | ACACBRETCPB2PPARGPPARD | |
| SCHEMBL5738130 | 1.00 | ACACB (0.45) | ACACBRETCPB2PPARGPPARD | |
| SCHEMBL31370459 | 0.89 | PDE10A (0.50) | ACACBRETCPB2PDE10ACKS1B | |
| SCHEMBL29749147 | 0.85 | RET (0.53) | ACACBRETCPB2PDE10ACKS1B | |
| SCHEMBL4789103 | 0.83 | DPP4 (0.50) | RETPANK3JAK3BTKCHRM4 | |
| SCHEMBL390147 | 0.83 | SYK (0.53) | RETPDE10ACKS1BSKP1SKP2 | |
| SCHEMBL389068 | 0.83 | SYK (0.53) | RETPDE10ACKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119053596-A | Heterocyclic compounds as kinase inhibitors, compositions and methods of use | 捷思英达控股有限公司 | 2024-11-29 | — | — | CN | disclosed |